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LRRC8A Rabbit Polyclonal Antibody

CAT: 0013-GTR17707133-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR17707133-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LRRC8A Rabbit Polyclonal Antibody
Product Name Alternative
LRC8A_HUMAN; LRRC8A; Leucine-rich repeat-containing protein 8A (HsLRRC8A) ; Swelling protein 1; KIAA1437; LRRC8; SWELL1; LRC8A_MOUSE; Leucine-rich repeat-containing protein 8A; Protein ebouriffe (ebo) ; LRC8A_RAT; Swelling protein 1 SWELL1; leucine rich repeat containing 8 VRAC subunit A; leucine rich repeat containing 8; leucine rich repeat containing 8 family member A
UniProt
Q8IWT6
Reactivity
Human
Immunogen
KLH conjugated synthetic peptide derived from human LRRC8A (84-180/810aa)
Target
LRRC8A
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Form
Liquid
Molecular Weight
94 kDa
References & Citations
Y Liu, X Li, C Huo, L Hou, X Jia, R Xu, J Yang, X Wang Caveolae Modulate the Activity of LRRC8‐Mediated VRAC by the Structural Membrane Protein Caveolin‐1 Y Liu, X Li, C Huo, L Hou, X Jia, R Xu, J Yang, X Wang, (2025)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Prediction Reactivity
Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep
Tested Applications
ELISA, ICC, IF, IHC-Fr, IHC-P, WB
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

UniProtKB · Q8IWT6

Volume-regulated anion channel subunit LRRC8A

LRC8A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8IWT6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRRC8A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6UXM2, Q8NCI0, Q9P2B1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinPhosphoprotein

Cellular component

Cell membraneLysosomeMembrane

Coding sequence diversity

Chromosomal rearrangement

Biological process

DifferentiationIon transportSpermatogenesisTransport

Molecular function

Ion channel

Domain

Leucine-rich repeatRepeatTransmembraneTransmembrane helix

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