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Vilobelimab

CAT: 0804-HY-P99520-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99520-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc[1].
CAS Number
2250440-41-4
Product Name Alternative
CaCP-29, IFX-1
UNSPSC
12352203
Target
Complement System; SARS-CoV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vilobelimab.html
Purity
99.95
Solubility
10 mM in DMSO
Smiles
[Vilobelimab]
Molecular Weight
(145.88 kDa)
References & Citations
[1]Michael Bauer, et al. Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study) . Crit Care Explor. 2021 Nov 17;3 (11) :e0577.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

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