(S,R,S)-AHPC-CO-C4-bromine

(S,R,S)-AHPC-CO-C4-bromine

• CAS Number: 2162120-79-6
• UNSPSC Description: (S,R,S)-AHPC-CO-C4-bromine is an E3 Ligase Ligand-linker Conjugate for PROTAC synthesis. (S,R,S)-AHPC-CO-C4-bromine is composed of an E3 Ligase Ligand (HY-125845) and a linker[1]
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-co-c4-bromine.html
• Smiles: BrCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O
• Molecular Weight: 593.58
• References & Citations: [1]Lv Y, et al. A Potent SOS1 PROTAC Degrader with Synergistic Efficacy in Combination with KRASG12C Inhibitor. J Med Chem. 2024 Feb 22;67(4):2487-2511.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported