APC Anti-Mouse LPAM-1 Antibody[DATK32]

• Background:

  DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors) . Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.

• Abbreviation:

  LPAM-1

• Gene ID:

  311144;25713

• UniProt:

  P26011; Q00651

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  Α4β7 Integrin; CD49d/β7; LPAM-1; ITGA4; ITGB7

• Clonality:

  Monoclonal

• Clone:

  DATK32

• Conjugation:

  APC

• Applications:

  FCM

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgG2a, κ