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Talsaclidine

CAT: 0804-HY-128855-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-128855-01Size:1 mg
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Description
Talsaclidine is a muscarinic agonist with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes[1][2][3][4]. Talsaclidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
147025-53-4
UNSPSC
12352005
Hazard Statement
H318
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/talsaclidine.html
Purity
98.75
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
C#CCO[C@@H]1[C@@H]2CCN(CC2)C1
Molecular Formula
C10H15NO
Molecular Weight
165.24
Precautions
H318
References & Citations
[1]Ensinger HA, et al. WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties. Life Sci. 1993;52 (5-6) :473-80.|[2]Wienrich M, et al. Pharmacodynamic profile of the M1 agonist talsaclidine in animals and man. Life Sci. 2001 Apr 27;68 (22-23) :2593-600.|[3]Walland A, et al. In vivo consequences of M1-receptor activation by talsaclidine. Life Sci. 1997;60 (13-14) :977-84.|[4]Walland A, et al. Compensation of muscarinic bronchial effects of talsaclidine by concomitant sympathetic activation in guinea pigs. Eur J Pharmacol. 1997 Jul 9;330 (2-3) :213-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
MAChR2; mAChR3

Alternative Products

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BA5510-5Talsaclidine
021242Talsaclidine Hydrochloride
A18571-50Talsaclidine 50mg
A18571-25Talsaclidine 25mg
A18571-5Talsaclidine 5mg
A18571-1Talsaclidine 1mg
A18571-100Talsaclidine 100mg

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