Vapreotide

• Description :

  Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.

• CAS Number :

  [103222-11-3]

• Product Name Alternative :

  RC160; BMY 41606

• UNSPSC :

  12352209

• Target :

  Neurokinin Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Vapreotide.html

• Purity :

  99.87

• Solubility :

  H2O : ≥ 100 mg/mL

• Smiles :

  O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCCN)=O)C(C)C)=O)C(N[C@H](C(N)=O)CC2=CNC3=CC=CC=C23)=O)NC([C@H](N)CC4=CC=CC=C4)=O)=O)CC5=CC=C(C=C5)O)N[C@@H]1CC6=CNC7=CC=CC=C67

• Molecular Formula :

  C57H70N12O9S2

• Molecular Weight :

  1131.37

• References & Citations :

  [1]Spitsin S et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20 (5) :247-55.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Peptides

• Clinical Information :

  Launched

• Isoform :

  NK1R