Vapreotide

• Description:

  Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.

• Product Name Alternative:

  RC160; BMY 41606

• UNSPSC:

  12352209

• Target:

  Neurokinin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Vapreotide.html

• Purity:

  99.87

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCCN)=O)C(C)C)=O)C(N[C@H](C(N)=O)CC2=CNC3=CC=CC=C23)=O)NC([C@H](N)CC4=CC=CC=C4)=O)=O)CC5=CC=C(C=C5)O)N[C@@H]1CC6=CNC7=CC=CC=C67

• Molecular Formula:

  C57H70N12O9S2

• Molecular Weight:

  1131.37

• References & Citations:

  [1]Spitsin S et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20 (5) :247-55.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Peptides

• Clinical Information:

  Launched

• Isoform:

  NK1R

• CAS Number:

  [103222-11-3]