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2'-O-MOE-rC

CAT: 0804-HY-W570885-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W570885-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA[1][2].
CAS Number
251647-54-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-o-moe-rc.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@H](N5C(N=C(NC(C6=CC=CC=C6)=O)C=C5)=O)O4
Molecular Formula
C49H58N5O10P
Molecular Weight
907.99
Precautions
H302, H315, H319, H335
References & Citations
[1]Prakash TP, et al. Comparing in vitro and in vivo activity of 2'-O-[2- (methylamino) -2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides. J Med Chem. 2008 May 8;51 (9) :2766-76.|[2]Li M, et al. Synthesis and cellular activity of stereochemically-pure 2'-O- (2-methoxyethyl) -phosphorothioate oligonucleotides. Chem Commun (Camb) . 2017 Jan 3;53 (3) :541-544.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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