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TAE648

CAT: 0804-HY-169396-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-169396-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAE648 is a target protein ligand of PROTAC SK-3-91 (Ligand for Target Protein for PROTAC). TAE648 can be used for synthesis PROTAC[1]. TAE648 decreases monolayer-cultured SKOV3ip1 cell viability[2].
CAS Number
2769753-10-6
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tae648.html
Purity
99.50
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(C=N1)=C(NC2=C(S(C(C)C)(=O)=O)C=CC=C2)N=C1NC(C=C3)=CC=C3N4CCNCC4
Molecular Formula
C23H27ClN6O2S
Molecular Weight
487.02
References & Citations
[1]Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183 (6) :1714-1731.e10. |[2]Cha HJ, et al. Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells. Int J Oncol. 2017 Apr;50 (4) :1279-1288.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T206608-01TAE648

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