Tolnaftate

• Description :

  Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. .

• Product Name Alternative :

  NP-27

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/Tolnaftate.html

• Concentration :

  10mM

• Purity :

  99.28

• Solubility :

  DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

• Smiles :

  S=C(OC1=CC=C2C=CC=CC2=C1)N(C)C3=CC=CC(C)=C3

• Molecular Formula :

  C19H17NOS

• Molecular Weight :

  307.41

• Precautions :

  H302

• References & Citations :

  [1]Ryder, N.S., I. Frank, and M.C. Dupont, Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate. Antimicrob Agents Chemother, 1986. 29 (5) : p. 858-60.|[2]Georgopapadakou, N.H. and A. Bertasso, Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother, 1992. 36 (8) : p. 1779-81.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [2398-96-1]