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5-Aminothalidomide-C9-Boc

CAT: 0804-HY-168277Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168277Size:1 Each
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Description
5-Aminothalidomide-C9-Boc is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC TRIB2 degrader-1.
CAS Number
3053782-32-1
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-aminothalidomide-c9-boc.html
Smiles
O=C(OC(C)(C)C)CCCCCCCCCNC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1
Molecular Formula
C27H37N3O6
Molecular Weight
499.60
References & Citations
[1]Wen C, et al. Discovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2. Eur J Med Chem. 2025 Jan 5;281:117016.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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