DB12055

CAT: 0804-HY-111074Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-111074Size:1 Each

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Description

DB12055 (MK-0767 analog) is a covalent SARS-CoV-2 3CL protease inhibitor. DB12055 has the potential for the study of dyslipidemia and diabetes mellitus[1].

CAS Number

934017-32-0

Product Name Alternative

MK-0767 analog

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/db12055.html

Smiles

O=C(NCC1=CC=C(C(F)(F)F)C=C1)C2=CC(CC(OC(N3)=O)C3=O)=CC=C2OC

Molecular Formula

C20H17F3N2O5

Molecular Weight

422.35

References & Citations

[1]Ronda K Rippley, et al. Human pharmacokinetics and interconversion of enantiomers of MK-0767, a dual PPARalpha/gamma agonist. J Clin Pharmacol. 2007 Mar;47 (3) :323-33.|[2]Ying Wang, et al. Multidimensional virtual screening approaches combined with drug repurposing to identify potential covalent inhibitors of SARS-CoV-2 3CL protease. J Biomol Struct Dyn. 2023;41 (24) :15262-15285.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

DB12055

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