NADase

CAT: 0804-HY-P2940-01Size: 1 gDry Ice: NoHazardous: No

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CAT#:0804-HY-P2940-01Size:1 g

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Description

NADase is an ectoenzyme/membrane-bound enzyme targeting nicotinamide adenine dinucleotide (NAD+) . NADase regulates intracellular NAD+ homeostasis by hydrolyzing NAD+ into nicotinamide mononucleotide (NMN) and ADP-ribose. NADase is promising for research of autoimmune diseases (e.g., systemic sclerosis, systemic lupus erythematosus) and aging-related disorders[1].

CAS Number

9032-65-9

UNSPSC

12352204

Target

NAMPT

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nadase.html

Solubility

10 mM in DMSO

Smiles

[NADase]

References & Citations

[1]Peclat TR, et al. The NADase enzyme CD38: an emerging pharmacological target for systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Curr Opin Rheumatol. 2020 Nov;32 (6) :488-496.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

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