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2-Phenylethyl isothiocyanate

CAT: 0804-HY-23155-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-23155-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternate might be via reduction in toxin content and breakdown of cell membrane integrity[1][2].
CAS Number
2257-09-2
Product Name Alternative
2-PE ITC
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H315, H317, H319, H334, H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/2-phenylethyl-isothiocyanate.html
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=C=NCCC1=CC=CC=C1
Molecular Formula
C9H9NS
Molecular Weight
163.24
Precautions
H302+H312+H332, H315, H317, H319, H334, H335
References & Citations
[1]B. J. Smith, et al. In vitro inhibition of soil microorganisms by 2-phenylethyl isothiocyanate. Plant Pathology. 4 October 2002;51 (5) :585-593.|[2]Zhang M, et al. 2-Phenylethyl Isothiocyanate Exerts Antifungal Activity against Alternaria alternata by Affecting Membrane Integrity and Mycotoxin Production. Toxins (Basel) . 2020 Feb 15;12 (2) :124.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2