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YM511

CAT: 0804-HY-105184-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105184-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively) . YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones[1].
CAS Number
148869-05-0
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ym511.html
Purity
99.73
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
BrC(C=C1)=CC=C1CN(N2C=NN=C2)C3=CC=C(C#N)C=C3
Molecular Formula
C16H12BrN5
Molecular Weight
354.20
References & Citations
[1]M Kudoh, et al. The potent and selective inhibition of estrogen production by non-steroidal aromatase inhibitor, YM511. J Steroid Biochem Mol Biol. 1995 Sep;54 (5-6) :265-71.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Aromatase/CYP19A1

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CatalogName
561441YM511

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