Products for Research Use Only
RegisterLogin

Nintedanib (Standard)

CAT: 0804-HY-50904R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-50904R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Nintedanib (Standard) is the analytical standard of Nintedanib. This product is intended for research and analytical applications. Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
CAS Number
656247-17-5
Product Name Alternative
BIBF 1120 (Standard)
UNSPSC
12352005
Target
FGFR; PDGFR; Reference Standards; VEGFR
Type
Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nintedanib-standard.html
Smiles
O=C1NC2=CC(C(OC)=O)=CC=C2/C1=C(NC3=CC=C(N(C(CN4CCN(C)CC4)=O)C)C=C3)\C5=CC=CC=C5
Molecular Formula
C31H33N5O4
Molecular Weight
539.62
References & Citations
[1]Hilberg F, et al. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res, 2008, 68 (12), 4774-4782.|[2]Roth GJ, et al. Design, synthesis, and evaluation of indolinones as triple angiokinase inhibitors and the discovery of a highly specific 6-methoxycarbonyl-substituted indolinone (BIBF 1120) . J Med Chem, 2009, 52 (14), 4466-4480.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-11106R-01Nintedanib esylate (Standard)
HY-Z0138RNintedanib impurity 41 (Standard)
HY-Z0127R-01Nintedanib impurity 8 (Standard)
HY-Z0128R-01Nintedanib impurity 9 (Standard)
HY-Z0013R-01Nintedanib impurity 7 (Standard)
HY-50904-01Nintedanib
HY-11106-01Nintedanib esylate
HY-50904SNintedanib-d3
HY-50904S2-01Nintedanib-d8
HY-Z4535-01Nintedanib impurity 6

Alternative Products

CatalogName
FM34144-01Nintedanib
C6370-5Nintedanib esylate

Popular Products