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N-Methylbenzamide

CAT: 0804-HY-135848-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-135848-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity[1][2].
CAS Number
613-93-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-methylbenzamide.html
Purity
99.93
Solubility
DMSO : ≥ 200 mg/mL
Smiles
O=C(NC)C1=CC=CC=C1
Molecular Formula
C8H9NO
Molecular Weight
135.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Kilburn JP, et al. N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors. Bioorg Med Chem. 2013 Oct 1;21 (19) :6053-62.|[2]Gate, E. N., et al. Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogs of N-methylformamide. Journal of Medicinal Chemistry, 1986, 29 (6), 1046–1052.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE10

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