PGD2-IN-1

• UNSPSC Description:

  PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d); has an IC50 of 0.3 nM.

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/PGD2-IN-1.html

• Purity:

  98.24

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O=C(O)C(C)(C)C1=CC=CC(C2=NC(OC)=NC(NCCC3=CC=C(Cl)C=C3Cl)=C2)=C1

• Molecular Weight:

  460.35

• References & Citations:

  [1]Lim, Sungtaek, et al. 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS. WO2006044732A2.|[2]Mu L, et al. Understanding DP receptor antagonism using a CoMSIA approach. Bioorg Med Chem Lett. 2011 Jan 1;21(1):66-75.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  885066-67-1