Adenosine 5′-diphosphoribose

• CAS Number:

  20762-30-5

• UNSPSC Description:

  Adenosine 5′-diphosphoribose (ADP ribose) is composed of an adenine base attached to a ribose sugar, which is in turn linked to two phosphate groups. Adenosine 5′-diphosphoribose is a key molecule involved in a variety of cellular processes, particularly in the response to DNA damage and the regulation of gene expression[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/adenosine-5-diphosphoribose.html

• Purity:

  98.21

• Solubility:

  H2O : 175 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OC[C@H]([C@H]([C@H](C=O)O)O)O)(O)=O)(O)=O

• Molecular Weight:

  559.32

• References & Citations:

  [1]Gibson BA, et al., New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nat Rev Mol Cell Biol. 2012 Jun 20;13(7):411-24.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  Phase 1