(S)-6-O-Desmethylnaproxen

• Product Name Alternative:

  (S)-6-Desmethyl Naproxen

• UNSPSC Description:

  (S)-6-O-Desmethylnaproxen ((S)-6-Desmethyl Naproxen) is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen). (S)-6-O-Desmethylnaproxen is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

• Target Antigen:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/s-6-o-desmethylnaproxen.html

• Purity:

  95.73

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  OC([C@H](C1=CC2=C(C=C(C=C2)O)C=C1)C)=O

• Molecular Weight:

  216.23

• References & Citations:

  [1]Miners, et al. Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen. Biochem. Pharmacol. 51(8), 1003-1008 (1996).

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  52079-10-4