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Natamycin

CAT: 0804-HY-B0133-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0133-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research[1][2].
CAS Number
7681-93-8
Product Name Alternative
Pimaricin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Endogenous Metabolite; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Natamycin.html
Purity
99.07
Solubility
DMSO : 15.38 mg/mL (ultrasonic; adjust pH to 3 with 1 M HCl) |H2O : < 0.1 mg/mL
Smiles
OC([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/C[C@@H](C)OC2=O)O[C@@](O[C@H](C)[C@@H](O)[C@@H]3N)([H])[C@H]3O)([H])O[C@](O)(C[C@H](C[C@]4([H])[C@@H](/C=C/2)O4)O)C[C@@H]1O)=O
Molecular Formula
C33H47NO13
Molecular Weight
665.73
Precautions
H302, H315, H319, H335
References & Citations
[1]Wu H, et al. SlnM gene overexpression with different promoters on natamycin production in Streptomyces lydicus A02. J Ind Microbiol Biotechnol. 2014 Jan;41 (1) :163-72.|[2]Yvonne Maria te Welscher, et al. Polyene antibiotic that inhibits membrane transport proteins. Proc Natl Acad Sci U S A. 2012 Jul 10;109 (28) :11156-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Macrolide; Microbial Metabolite

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CatalogName
A5786-5.1Natamycin

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