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Anumigilimab

CAT: 0804-HY-P99440-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99440-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anumigilimab (CSL-324) is an human IgG4 mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation[1][2].
CAS Number
2416593-08-1
Product Name Alternative
CSL-324
UNSPSC
12352203
Target
C-Fms; JAK; STAT
Type
Inhibitory Antibodies
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anumigilimab.html
Purity
98.43
Solubility
10 mM in DMSO
Smiles
[Anumigilimab]
Molecular Weight
(143.86 kDa)
References & Citations
[1]Markota Čagalj A, et al. New and Emerging Targeted Therapies for Hidradenitis Suppurativa. Int J Mol Sci. 2022 Mar 29;23 (7) :3753. |[2]Rosales Santillan M, et al. Biologic therapies for the treatment of hidradenitis suppurativa. Expert Opin Biol Ther. 2020 Jun;20 (6) :621-633. |[3]Scalzo-Inguanti K, et al., A neutralizing anti-G-CSFR antibody blocks G-CSF-induced neutrophilia without inducing neutropenia in nonhuman primates. J Leukoc Biol. 2017 Aug;102 (2) :537-549.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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