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Dalutrafusp alfa

CAT: 0804-HY-P99841-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99841-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dalutrafusp alfa (AGEN-1423; GS-1423) is a specific bifunctional antibody against CD73 and TGF-β, which is involved in the immunosuppressive pathway[1].
CAS Number
2419918-89-9
Product Name Alternative
AGEN-1423; GS-1423
UNSPSC
12352203
Target
CD73; TGF-β Receptor
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/dalutrafusp-alfa.html
Purity
96.83
Solubility
10 mM in DMSO
Smiles
[Dalutrafuspalfa]
Molecular Weight
(178.15 kDa)
References & Citations
[1]Anthony W Tolcher, et al. Phase 1 first-in-human study of dalutrafusp alfa, an anti-CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors. J Immunother Cancer. 2023 Feb;11 (2) :e005267.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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