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Serplulimab

CAT: 0804-HY-P99118-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99118-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serplulimab (HLX 10) is a humanized anti-PD-1 monoclonal antibody. Serplulimab can inhibit tumor growth, regulate the tumor microenvironment, and has anti-tumor activity. Serplulimab can be used in the research of cancer such as lung cancer and colon cancer[1][2].
CAS Number
2231029-82-4
Product Name Alternative
HLX 10
UNSPSC
12352203
Target
Akt; PD-1/PD-L1; STAT
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/serplulimab.html
Purity
99.30
Solubility
H2O
Smiles
[Serplulimab]
Molecular Weight
(144.18 kDa)
References & Citations
[1]Lee A. Serplulimab: First Approval. Drugs. 2022 Jul;82 (10) :1137-1141.|[2]Zhang Y, et al. Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or LAG3 inhibitor in preclinical tumor immunotherapy studies. MAbs. 2024 Jan-Dec;16 (1) :2419838.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Isoform
Akt1; Akt2; Akt3; STAT3

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