O-Desmethyltramadol (hydrochloride)

CAT:

804-HY-109054A-03

Size:

1 mg

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CAS Number: 185453-02-5
UNSPSC Description: O-Desmethyltramadol (hydrochloride) is a primary active metabolite of Tramadol. O-Demethyltramadol is mainly responsible for its µ-opioid receptor-related analgesic effect. Tramadol is metabolized to O-Demethyltramadol mainly by the cytochrome P450 (CYP) 2D6 enzyme[1].
Target Antigen: Drug Metabolite
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/o-desmethyltramadol-hydrochloride.html
Purity: 97.64
Solubility: 10 mM in DMSO
Smiles: OC1=CC=CC([C@]2(O)[C@@H](CN(C)C)CCCC2)=C1.Cl
Molecular Weight: 285.81
References & Citations: [1]Lee J, et al. Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6. Drug Des Devel Ther. 2019;13:1751-1761.
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
Clinical Information: No Development Reported

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