Apecotrep

CAT: 0804-HY-148129-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-148129-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Apecotrep (TRPC6-IN-3) (compound 17) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. Apecotrep modulates not only intracellular calcium concentration, but also membrane potential by modulating the flux of cations including calcium and sodium ions. Apecotrep can be used in research of respiratory system[1].

CAS Number

2311863-36-0

Product Name Alternative

TRPC6-IN-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/trpc6-in-3.html

Purity

99.17

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N1CCC(C2=NN=C(N)C=C2)CC1)C3=NC=C(OC4=CC=C(F)C=C4)C(OC)=C3

Molecular Formula

C22H22FN5O3

Molecular Weight

423.44

Precautions

H302, H315, H319, H335

References & Citations

[1]Thierry B, et, al. Inhibitors of TRPC6 for treating respiratory conditions. WO2021209510.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Apecotrep

Popular Products