Chitohexaose (hexahydrochloride)

Chitohexaose (hexahydrochloride)

• CAS Number: 127171-88-4
• UNSPSC Description: Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites of TLR4 and inhibits LPS induced inflammation[1][2].
• Target Antigen: Toll-like Receptor (TLR)
• Type: Natural Products
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/chitohexaose-hexahydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H](O[C@H]1O[C@@H]([C@@H]([C@H]2N)O)[C@H](O[C@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@@H](N)C=O)CO)[C@H]([C@@H]([C@H]1N)O)O[C@@H]([C@@H]([C@H]3O)N)O[C@@H]([C@H]3O[C@@H]([C@@H]([C@H]4O)N)O[C@@H]([C@H]4O[C@@H]([C@@H]([C@H]5O)N)O[C@@H]([C@H]5O)CO)CO)CO.Cl.Cl.Cl.Cl.Cl.Cl
• Molecular Weight: 1203.72
• References & Citations: [1]Qini Zhao, et al. Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties. Oxid Med Cell Longev. 2020 Apr 11;2020:2394704.|[2]Santosh K Panda, et al. Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia. PLoS Pathog. 2012;8(5):e1002717.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported