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TP0438836

CAT: 0804-HY-124664Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124664Size:1 Each
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Description
TP0438836 (compound 30b) is a SGLT1 inhibitor, with IC50 values ​​of 28 nM and 7 nM for hSGLT1 and hSGLT2, respectively. TP0438836 can be used in diabetes research[1].
CAS Number
957772-01-9
UNSPSC
12352005
Target
SGLT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tp0438836.html
Smiles
O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)CCNC(NC(CO)(CO)CO)=O)=C(C=C2O)C)O[C@@H]([C@H]([C@@H]1O)O)CO
Molecular Formula
C27H38N2O10
Molecular Weight
550.60
References & Citations
[1]Kuroda S, et al. Discovery of a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor (TP0438836) for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2018 Dec 1;28 (22) :3534-3539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGLT1; SGLT2

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CatalogName
MBS5810801TP0438836

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