Hydroxytyrosol

CAT: 0804-HY-N0570-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0570-01Size:5 mg
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Description
Hydroxytyrosol (DOPET) is a phenol found in the olive oil. Hydroxytyrosol can alleviate oxidative stress and improve mitochondrial function, thereby exerting neuroprotective effects. Hydroxytyrosol can induce cancer cells apoptosis via inducing ROS production. Hydroxytyrosol shows antibacterial and antiviral effect. Hydroxytyrosol can be used for the researches of cancer, infection, inflammation, immunology, metabolic, neurological and cardiovascular disease, such as colon cancer, diabetes, Alzheimer's Disease and atherosclerosis[1][2][3][4][5][6][7][8].
CAS Number
[10597-60-1]
Product Name Alternative
DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Bacterial; Reactive Oxygen Species (ROS) ; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hydroxytyrosol.html
Purity
99.85
Solubility
DMSO : 125 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCO)C=C1O
Molecular Formula
C8H10O3
Molecular Weight
154.16
Precautions
H302
References & Citations
[1]Alblihed MA, et al. Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis in mice. Hum Exp Toxicol. 2021 Feb;40 (2) :342-354. |[2]Acín S, et al. Hydroxytyrosol administration enhances atherosclerotic lesion development in apo E deficient mice. J Biochem. 2006 Sep;140 (3) :383-91.|[3]Peng Y, et al. Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice. Mol Nutr Food Res. 2016 Nov;60 (11) :2331-2342.|[4]Marina Aparicio-Soto, et al. Dietary hydroxytyrosol and hydroxytyrosyl acetate supplementation prevent pristane-induced systemic lupus erythematous in mice, Journal of Functional Foods, Volume 29, 2017, Pages 84-92.|[5]Masih Ghalandari, et al. Antimicrobial effect of Hydroxytyrosol, Hydroxytyrosol Acetate and Hydroxytyrosol Oleate on Staphylococcus Aureus and Staphylococcus Epidermidis. ELECTRON J GEN MED, Volume 15, Issue 4, August 2018, Article No: em46|[6]Reyes JJ, et al. Neuroprotective Effect of Hydroxytyrosol in Experimental Diabetes Mellitus. J Agric Food Chem. 2017 Jun 7;65 (22) :4378-4383.|[7]Sun L, et al. Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation. Food Funct. 2014 Aug;5 (8) :1909-14.|[8]Paolacci S, et al. In vitro and clinical studies on the efficacy of α-cyclodextrin and hydroxytyrosol against SARS-CoV-2 infection. Eur Rev Med Pharmacol Sci. 2021 Dec;25 (1 Suppl) :81-89.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 4
Isoform
Microbial Metabolite

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