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Artemitin

CAT: 0804-HY-N3017-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3017-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Artemitin is a flavonoid neuroanesthetic agent with moderate cytotoxicity. Artemitint has selective inhibitory activity against Meth-A sarcoma cells with an ED50 of 5-10 μg/mL, and has no significant effect on LLC lung cancer cells. Artemitin exerts anticancer activity by affecting cell proliferation signaling pathways, and also has potential anti-inflammatory and neuroprotective effects. Artemitin exhibits a dose-dependent antinociceptive effect in the mouse hot plate test, with an ED50 of 1.6 μg/kg, and has analgesic activity[1][2][3].
CAS Number
479-90-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/artemitin.html
Purity
99.97
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(O)C(OC)=C(OC)C=C2OC(C3=CC(OC)=C(OC)C=C3)=C1OC
Molecular Formula
C20H20O8
Molecular Weight
388.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Ma CM, et al. Triterpenes and lignans from Artemisia caruifolia and their cytotoxic effects on meth-A and LLC tumor cell lines. Chem Pharm Bull (Tokyo) . 2001 Feb;49 (2) :183-7.|[2]Han X, et al. Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study. Biomed Chromatogr. 2018 Dec;32 (12) :e4356.|[3]Qnais, Esam, et al. Antinociceptive effect of two flavonoids from Aloysia triphylla L. Jordan Journal of Biological Sciences 2.4 (2009) : 167-170.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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