Neamine

• Description :

  Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection; Neurological Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/neamine.html

• Purity :

  99.96

• Solubility :

  H2O : 100 mg/mL (ultrasonic)

• Smiles :

  O[C@H]([C@H]1O)[C@@H]([C@H](C[C@H]1N)N)O[C@H]([C@@H]([C@H]2O)N)O[C@@H]([C@H]2O)CN

• Molecular Formula :

  C12H26N4O6

• Molecular Weight :

  322.36

• Precautions :

  H315, H319

• References & Citations :

  [1]Ya-Ping Liu, et al. Neamine Inhibits Growth of Pancreatic Cancer Cells in Vitro and in Vivo. J Huazhong Univ Sci Technolog Med Sci. 2016 Feb;36 (1) :82-87.|[2]R Ning, et al. Neamine Induces Neuroprotection After Acute Ischemic Stroke in Type One Diabetic Rats. Neuroscience. 2014 Jan 17;257:76-85.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Aminoglycoside

• CAS Number :

  [3947-65-7]