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Semorinemab

CAT: 0804-HY-P99399-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99399-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23) . Semorinemab binds with human Tau with a Kd value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease[1].
CAS Number
2159141-27-0
Product Name Alternative
RG 6100; RO7105705; MTAU-9937A
UNSPSC
12352203
Target
Tau Protein
Type
Inhibitory Antibodies
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/semorinemab.html
Purity
99.36
Solubility
10 mM in DMSO
Smiles
[Semorinemab]
Molecular Weight
(145.1 kDa)
References & Citations
[1]Ayalon G, et al. Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease. Sci Transl Med. 2021 May 12;13 (593) :eabb2639.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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