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Zymosan

CAT: 0793-15-1024-100Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0793-15-1024-100Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Specificity: TLR2 and Dectin-1 agonist Zymosan, an insoluble preparation of cell wall from Saccharomyces cerevisiae, activates macrophages via TLR2. TLR2 cooperates with TLR6 and CD14 in response to zymosan. Zymosan is also recognized by Dectin-1, a phagocytic receptor expressed on macrophages and dendritic cells, which collaborates with TLR2 and TLR6 enhancing the immune responses triggered by the recognition of Zymosan by each receptor.
Applications
Functional Assay
Storage Conditions
Zymosan is stable at 4°C for 6 months or at -20°C for 12 months
Applications Notes
Solubility: Insoluble (resuspended zymosan results in a cloudy suspension) . Vortex to homogenize, Add 10 ml endotoxin free water Stimulation of TLR2 can be achieved with 10 μg/ml zymosan. Stimulation of Dectin-1 can be achieved with 1 - 10 μg/ml zymosan.

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Alternative Products

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JAA01072Zymosan
A9934-100Zymosan A
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59008-84Zymosan Depleted
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B2013371Zymosan A (Highly Pure)
HY-159069-01Zymosan (ZM), 95%
B2016688Green Zymosan A Fluorescent Particles
B400Zymosan Complement Assay Reagents
Z-9500-01Zymosan A (from Saccharomyces cerevisiae)

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