Flagellin

• Description :

  Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system via Toll-like receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4) . Source: Recombinant Flagellin from Salmonella typhimurium Endotoxin level: <0.5 EU/μg Specificity: TLR5 agonist

• Product Name Alternative :

  FliC

• Reactivity :

  Mouse, Human

• Applications :

  Functional Assay

• Components :

  0.1 mg/ml in endotoxin-free water

• Storage Conditions :

  Upon receipt, store at -20°C (Stable for at least 6 months) . Avoid frequent freeze/thaw cycles.

• Applications Notes :

  TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1μg /mouse.