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Capecitabine

CAT: 0804-HY-B0016-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0016-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase.
CAS Number
154361-50-9
UNSPSC
12352005
Hazard Statement
H341, H350, H360, H402
Target
Apoptosis; DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Capecitabine.html
Purity
99.99
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=C(C(NC(OCCCCC)=O)=NC2=O)F)O[C@@H]1C
Molecular Formula
C15H22FN3O6
Molecular Weight
359.35
Precautions
H341, H350, H360, H402
References & Citations
[1]PharmD CM, et al. Capecitabine: A review. Clinical Therapeutics. 2005 Jan; 27 (1) : 23-44.|[2]Guichard SM, et al. Gene expression predicts differential capecitabine metabolism, impacting on both pharmacokinetics and antitumour activity. Eur J Cancer. 2008 Jan;44 (2) :310-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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