Mouse CD70 Protein, hFc Tag

CAT: 0793-32-18539-100Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0793-32-18539-100Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Description :Recombinant mouse CD70 protein with N-terminal human Fc tagBackground: Predicted to enable cytokine activity and protease binding activity. Predicted to be involved in several processes, including B cell proliferation; T cell mediated immunity; and extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in Meckel's cartilage; hip; and skeleton. Human ortholog (s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 molecule) . [provided by Alliance of Genome Resources, Apr 2022]Description: Recombinant mouse CD70 protein with N-terminal human Fc tagMolecular Characterization: hFc (Glu99-Ala330) Mouse CD70 (Ser45-Pro195) Molecular Weight :The protein has a predicted molecular mass of 42.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mCD70 is approximately 35-70 kDa due to glycosylation.Tag :N-Human Fc Tag

Product Name Alternative

Cd27l; CD27LG; Tnfsf7; Tnlg8a

UniProt

O55237

Host

HEK293

Target Antigen

CD70

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

UniProtKB · O55237

CD70 antigen

CD70_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: O55237
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Cd70
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: —
Processing: —
Secondary accessions: —

Protein keywords

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Technical term

Reference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

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