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Mouse CGRP Protein, hFc Tag

CAT: 0793-32-18537-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0793-32-18537-100Size:100 µg
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Description
Description :Recombinant mouse CGRP protein with C-terminal human Fc tagBackground : This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. Molecular Characterization: mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of mCGRP-hFc is approximately 25-35 kDa due to glycosylation.Tag :C-Human Fc Tag
Product Name Alternative
CA; Ct; Ctn; Calc; Calca; CGRP1; Calc1; CGRP-1
UniProt
Q99JA0
Host
HEK293
Target Antigen
CGRP
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

UniProtKB · Q99JA0

Calcitonin gene-related peptide 1

CALCA_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q99JA0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Calca
Protein existence
2: Evidence at transcript level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
CGRP1
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

AmidationCleavage on pair of basic residuesDisulfide bond

Molecular function

Hormone

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal

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