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CFB-b Human

CAT: 0793-32-13750-10Size: 10 µgDry Ice: NoHazardous: No
CAT#:0793-32-13750-10Size:10 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source:Human Plasma.Physical Appearance:Sterile filtered solution.Biological ActivitynullComplement Factor B, also known as CFB, encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also, Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.CFB-b Human produced in Human Plasma having a molecular mass of 33 kDa.
Product Name Alternative
Complement factor B (EC:3.4.21.47), C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, Complement Factor B, BFD, AHUS4, BF, BFD, CFAB, FB, FBI12, H2-Bf.
Purification
Greater than 95.0% as determined by SDS-PAGE.
Format
CFB-b solution (1mg/mL) contains Phosphate-buffered saline, pH 7.3.
Storage Conditions
CFB-b Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

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