CD209 Human

Source:Sf9, Baculovirus cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivitynullCD209 (a member of the C-typelectin family) is Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) andtakes part in initiation of primary immune response.CD209has a high affinity for theICAM3 molecule and binds various microorganisms by recognizing high-mannose-containing glycoproteins ontheir envelopes and especially functions as receptor for several viruses such as HIV and Hepatitis C. Along with other C-typelectins, CD209is involved in recognition of tumors by dendritic cells.CD209also initiatesnatural immunity bymodulating toll-like receptors.CD209 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 587 amino acids (60-404 a.a) and having a molecular mass of 66.5kDa.CD209 is fused to a 239 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.

CD209 antigen, CD209 antigen isoform 1, C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CD209, CLEC4L, CDSIGN

Greater than 90.0% as determined by SDS-PAGE.

The CD209 solution (0.25mg/mL) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4) .

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.