Products for Research Use Only
RegisterLogin

SERPINA5 Human, Active

CAT: 0793-32-13403-1Size: 1 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0793-32-13403-1Size:1 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Source: Escherichia Coli.Sterile Filtered colorless solution.SERPINA5 up regulates TAFI activation by inhibiting the protein C activation. SERPINA5 is a significant regulator in the equilibrium between coagulation and fibrinolysis by differentially inhibiting the activation of TAFI and of Protein-C. SERPINA5 belongs to the serpin serine proteinase inhibitor family. SERPINA5 protein inhibits plasminogen activators as well as activated protein C. SERPINA5 is secreted in plasma & liver. SERPINA5 is involved in cell inflammation, proliferation, apoptosis, tumour cell migration, invasion, and metastasis. Moreover, SERPINA5 controls the invasive potential of renal cell carcinoma by inhibiting urinary plasminogen activator secreted by the cells. SERPINA5 participtes in regulating key serine proteases which are involved in metastatic prostate disease.SERPINA5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 408 amino acids (20-406 a.a) and having a molecular mass of 45.9kDa.SERPINA5 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Name Alternative
Serpin Family A Member 5, Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5, Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5, Acrosomal Serine Protease Inhibitor 3 4 Protein C Inhibitor, PLANH3, PAI-3, PROCI, PAI3
Applications
Functional Assay
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
SERPINA5 protein solution (0.5mg/mL) contains 150mM NaCl, 10% glycerol & 20 mM MES buffer (pH6.0) .
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Applications Notes
Measured by its ability to inhibit Thrombin cleavage of substrate Boc-VPR-AMC. The IC50 for this effect is less or equal to 2 nM.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MHRHHPREMK KRVEDLHVGA TVAPSSRRDF TFDLYRALAS AAPSQNIFFS PVSISMSLAM LSLGAGSSTK MQILEGLGLN LQKSSEKELH RGFQQLLQEL NQPRDGFQLS LGNALFTDLV VDLQDTFVSA MKTLYLADTF PTNFRDSAGA MKQINDYVAK QTKGKIVDLL KNLDSNAVVI MVNYIFFKAK WETSFNHKGT QEQDFYVTSE TVVRVPMMSR EDQYHYLLDR NLSCRVVGVP YQGNATALFI LPSEGKMQQV ENGLSEKTLR KWLKMFKKRQ LELYLPKFSI EGSYQLEKVL PSLGISNVFT SHADLSGISN HSNIQVSEMV HKAVVEVDES GTRAAAATGT IFTFRSARLN SQRLVFNRPF LMFIVDNNIL FLGKVNRP.

Related Products

CatalogName
32-13340-10NME3 Human, Active
32-13269-1IMPAD1 Human, Active
32-13269-5IMPAD1 Human, Active
32-13182-2CSTB Human, Active
32-6994-5PGK2 Human, Active
32-6686-10CA8 Human, Active
32-6992-10PGK1 Human, Active
32-6982-10GUK1 Human, Active
32-6684-2CA1 Human, Active
32-6951-10ADK Human, Active

Alternative Products

CatalogName
abx680391-01Human Protein C Inhibitor (SERPINA5) Protein (Active)
AHC14202Recombinant Human SERPINA5 Protein, C-His (Active)
AHC14201Recombinant Human SERPINA5 Protein, C-10*His (Active)
pro-2523SERPINA5, Active
OM305931-01SERPINA5 Human
P518270SerpinA5; SERPINA5 Protein (C-His, Human)
PKSH033034-01Recombinant Human SerpinA5/SERPINA5 Protein (His Tag)
CRH3396-01SERPINA5 siRNA (Human)
P4508-01Recombinant Human SERPINA5
GTR18905976-01Human SERPINA5 protein

Popular Products