RegisterLogin

MYBPC3 Human

CAT: 0793-32-13328-10Size: 10 µgDry Ice: NoHazardous: No
CAT#:0793-32-13328-10Size:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Source: Escherichia Coli.Filtered White lyophilized (freeze-dried) powder.Myosin Binding Protein C, Cardiac (MYBPC3) is the cardiac isoform of myosin-binding protein C expressed exclusively in heart muscle. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase upon adrenergic stimulation may be associated with modulation of cardiac contraction. MYBPC3 gene mutations are one of the causes of familial hypertrophic cardiomyopathy. In vitro MYBPC3 binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. MYBPC3 may modulate muscle contraction or it may have a more structural role.MYBPC3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Met1-Phe271) containing 281 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 29.6kDa.
Product Name Alternative
Myosin Binding Protein C Cardiac, C-Protein Cardiac Muscle Isoform, Myosin-Binding Protein C Cardiac, Cardiac MyBP-C, CMD1MM, LVNC10, MYBP-C, CMH4, FHC, MYBPC3.
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
MYBPC3 was filtered (0.4μm) and lyophilized in 20mM Tris buffer and 50mM NaCl, pH 7.5.It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. MYBPC3 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Storage Conditions
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Amino Acids
MKHHHHHHASMPEPGKKPVS AFSKKPRSVE VAAGSPAVFE AETERAGVKV RWQRGGSDIS ASNKYGLATE GTRHTLTVRE VGPADQGSYA VIAGSSKVKF DLKVIEAEKA EPMLAPAPAP AEATGAPGEA PAPAAELGES APSPKGSSSA ALNGPTPGAP DDPIGLFVMR PQDGEVTVGG SITFSARVAG ASLLKPPVVK WFKGKWVDLS SKVGQHLQLH DSYDRASKVY LFELHITDAQ PAFTGSYRCE VSTKDKFDCS NFNLTVHEAM GTGDLDLLSA F.

Related Products

CatalogName
32-190044-50IL-6 (human) :Fc (human) (Recombinant)
32-6527-25PLGF3 Human
32-6547-10RBP3 Human
32-6549-50SAA Human
32-6569-10TNFRSF8 Human
32-6569-2TNFRSF8 Human
32-6572-10TNFRSF10A Human
32-6572-2TNFRSF10A Human
32-6602-25CXCL16 Human
32-6604-10FAM19A5 Human

Alternative Products

CatalogName
OM305291-01MYBPC3 Human
MBS7610487-01Recombinant Human MYBPC3
MBS8239052-01MYBPC3 siRNA (Human)
abx925099-01Human MYBPC3 siRNA
31203051MYBPC3 Adenovirus (Human)
ELA-E9964hHuman MYBPC3 ELISA Kit
HY-P71532-01MYBPC3, Human (His-SUMO)
OPCA04461-20UGMYBPC3 Recombinant Protein (Human)
HY-P71532A-01MYBPC3, Human (HEK293, His)
MBS8415664-01Human MYBPC3 Protein Lysate

Popular Products