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Human Bone Morphogenetic Protein-2 (AF)

CAT: 0793-32-12020-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0793-32-12020-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source: Genetically modified E.coli. Predicted MW: Dimer, 13.0/26.1 kDa (115/230 aa) Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Product Name Alternative
BMP-2A, BMP2A
Gene Name
BMP2
Gene ID
650
UniProt
P12643
Purification
Reducing and Non-Reducing SDS PAGE at >= 95%
Components
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) Sterile water at 0.1 mg/mL
Shipping Conditions
Room temperature
Storage Conditions
Store at -20°C
Applications Notes
Endotoxin: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. Biological Activity was determined by Alkaline phosphatase activity induced in ATDC-5 cells at <= 250 ng/mL; >= 4.0 x 10^3 units/mg .Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
Amino Acids
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

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Alternative Products

CatalogName
PROTP12643-7-100ugHuman recombinant BMP-2 (Bone morphogenetic protein-2) protein, AF
545454Bone Morphogenetic Protein 2
abx262193-01Bone Morphogenetic protein-2 Protein
MBS6408644-01BMP2 (Bone Morphogenetic Protein 2, BMP 2A, BMP 2, BMP2A, bone morphogenetic Protein 2, Bone morphogenetic Protein 2A) (APC)
209774-01BMP2 (Bone Morphogenetic Protein 2, BMP 2A, BMP 2, BMP2A, bone morphogenetic Protein 2, Bone morphogenetic Protein 2A) discontinued
052065BMP-2/BMP-4 (Bone Morphogenetic Protein 2/Bone Morphogenetic Protein 4)
MBS6408653-01BMP2 (Bone Morphogenetic Protein 2, BMP 2A, BMP 2, BMP2A, bone morphogenetic Protein 2, Bone morphogenetic Protein 2A) (PE)
MBS6408645-01BMP2 (Bone Morphogenetic Protein 2, BMP 2A, BMP 2, BMP2A, bone morphogenetic Protein 2, Bone morphogenetic Protein 2A) (Biotin)
MBS6408647-01BMP2 (Bone Morphogenetic Protein 2, BMP 2A, BMP 2, BMP2A, bone morphogenetic Protein 2, Bone morphogenetic Protein 2A) (HRP)
MBS6408646-01BMP2 (Bone Morphogenetic Protein 2, BMP 2A, BMP 2, BMP2A, bone morphogenetic Protein 2, Bone morphogenetic Protein 2A) (FITC)

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