Recombinant Human Eukaryotic Translation Initiation Factor 4E/EIF4E

CAT: 0793-32-8322-50Size: 50 µgDry Ice: NoHazardous: No

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CAT#:0793-32-8322-50Size:50 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Source: E. coli. MW :25.1kD. Recombinant Human EIF4E is produced by our E.coli expression system and the target gene encoding Met1-Val217 is expressed. Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Gene Name

EIF4E

Gene ID

1977

UniProt

P06730

Components

Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.

Shipping Conditions

The product is shipped at ambient temperature.

Storage Conditions

Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.

Applications Notes

Endotoxin : Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

Amino Acids

MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

UniProtKB · P06730

Eukaryotic translation initiation factor 4E

IF4E_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P06730
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF4E
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-4E, eIF4E
EC number: —
Processing: —
Secondary accessions: B7Z6V1, D6RCQ6, Q96E95

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Disease

AutismAutism spectrum disorder

Cellular component

CytoplasmNucleus

Biological process

Host-virus interactionmRNA transportProtein biosynthesisTranslation regulationTransport

Molecular function

Initiation factorRNA-binding

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Alternative Products

Catalog	Name
480052	EIF4E (Eukaryotic Translation Initiation Factor 4E)
V9192-20UG	Eukaryotic translation initiation factor 4E Antibody / EIF4E
abx302090-01	Eukaryotic Translation Initiation Factor 4E (EIF4E) Antibody
AP75933-01	Recombinant Human Eukaryotic Translation Initiation Factor 4E/EIF4E
MBS1146842-01	Recombinant Rat Eukaryotic translation initiation factor 4E (Eif4e)
CSB-YP007556HU-01	Recombinant Human Eukaryotic translation initiation factor 4E (EIF4E)
E8949-40U-01	Eukaryotic Translation Initiation Factor 4E (eIF4E, eIF4EL1) discontinued
MBS1327231-01	Recombinant Bovine Eukaryotic translation initiation factor 4E (EIF4E)
abx680260-01	Mouse Eukaryotic Translation Initiation Factor 4E (EIF4E) Protein