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PRDX1 Mouse

CAT: 0793-32-6896-2Size: 2 µgDry Ice: NoHazardous: No
CAT#:0793-32-6896-2Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.PRDX1 is part of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. PRDX1 is an important protector of red blood cells against reactive oxygen species and in tumor prevention.PRDX1 is antioxidant protective in cells, and contributes to the antiviral activity of CD8 (+) T-cells. PRDX1 has a proliferative effect and is involved in cancer development or progression.Peroxiredoxin-1 is plays a role in redox regulation of the cell. Peroxiredoxin decreases peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. Peroxiredoxin is involved in eliminating peroxides generated during metabolism. Peroxiredoxin participates in the signaling cascades of growth factors and TNF-alpha by regulating the intracellular concentrations of h (2) o (2) .PRDX1 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 207 amino acids (1-199a.a.) and having a molecular mass of 23.2kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa) . PRDX1 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Product Name Alternative
Peroxiredoxin-1, Macrophage 23 kDa stress protein, Osteoblast-specific factor 3, OSF-3, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2.
Applications
Functional Assay
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
PRDX1 protein solution (0.5mg/mL) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Applications Notes
Specific activity is >2,500 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25°C for minute.
Amino Acids
MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVNK SKEYFSKQKL EHHHHHH.

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