Products for Research Use Only
RegisterLogin

LGMN Human

CAT: 0793-32-6834-10Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0793-32-6834-10Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Source: Sf9, Baculovirus cells.Sterile filtered colorless solution. Legumain, also known as LGMN, is a cysteine endopeptidase which demonstrates strict specificity for hydrolysis of asparaginyl bonds. Furthermore, LGMN can also cleave aspartyl bonds slowly, in particular under acidic conditions. LGMN plays an essential role in the endosomal/lysosomal degradation system as the Legumain deficiency causes the accumulation of pro cathepsins B, H & L, another group of lysosomal cysteine proteases. Furthermore, over expression of LGMN in tumors is important for invasion/metastasis.LGMN produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (18-433 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 422 amino acids and having a molecular mass of 48.4kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa) .LGMN is purified by proprietary chromatographic techniques.
Product Name Alternative
Legumain, PRSC1, Protease, Cysteine, 1 (Legumain), Asparaginyl Endopeptidase, Protease, Cysteine 1, EC 3.4.22.34, Cysteine Protease 1, LGMN1, AEP.
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
LGMN protein solution (1mg/mL) contains Phosphate buffered saline (pH7.4) and 10% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Amino Acids
VPIDDPEDGG KHWVVIVAGS NGWYNYRHQA DACHAYQIIH RNGIPDEQIV VMMYDDIAYS EDNPTPGIVI NRPNGTDVYQ GVPKDYTGED VTPQNFLAVL RGDAEAVKGI GSGKVLKSGP QDHVFIYFTD HGSTGILVFP NEDLHVKDLN ETIHYMYKHK MYRKMVFYIE ACESGSMMNH LPDNINVYAT TAANPRESSY ACYYDEKRST YLGDWYSVNW MEDSDVEDLT KETLHKQYHL VKSHTNTSHV MQYGNKTIST MKVMQFQGMK RKASSPVPLP PVTHLDLTPS PDVPLTIMKR KLMNTNDLEE SRQLTEEIQR HLDARHLIEK SVRKIVSLLA ASEAEVEQLL SERAPLTGHS CYPEALLHFR THCFNWHSPT YEYALRHLYV LVNLCEKPYP LHRIKLSMDH VCLGHYHHHH HH.

Related Products

CatalogName
32-6835-2LGMN Mouse
32-6835-10LGMN Mouse
32-190044-50IL-6 (human) :Fc (human) (Recombinant)
32-13810-250VWA2 Human
32-13808-10ASPSCR1 Human
32-13808-2ASPSCR1 Human
32-13802-2SPON1 Human
32-13792-2RAET1L Human
32-13785-2NCAM1 Human
32-13784-50MUC16 Human

Alternative Products

CatalogName
PT-A03333-01LGMN Human
abx902970-01Human LGMN siRNA
26488051LGMN Adenovirus (Human)
GTR18882162-01Human LGMN protein
Z05573-500LGMN, His, Human
CRH3802-01LGMN siRNA (Human)
P6347-01Recombinant Human LGMN
CRP1898-01Recombinant Human LGMN Protein
abx166733-01Human Legumain (LGMN) Protein
abx953802-01Human LGMN shRNA Plasmid

Popular Products