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Recombinant Human Jun Dimerization Protein 2

CAT: 0793-32-4034-5Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0793-32-4034-5Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. JDP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 187 amino acids (1-163 a.a) and having a molecular mass of 21.2kDa.JDP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Jun dimerization protein 2 (JDP2) is a component of the AP-1 transcription factor which inhibits transactivation mediated by the Jun family of proteins. JDP2 is involved in various transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. In addition, JDP2 can act as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. JDP2 controls transcription via direct regulation of the modification of histones and the assembly of chromatin.
Product Name Alternative
Jun dimerization protein 2||JDP2||JUNDM2||Progesterone Receptor Co-Activator.
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
JDP2 protein solution (0.25mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 1mM DTT, 1mM EDTA and 250mM imidazole.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK.

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