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CD46 Recombinant Protein

CAT: 0793-32-3474-20Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0793-32-3474-20Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : E.coli. CD46 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (35-313 a.a) and having a molecular mass of 33.8kDa. CD46 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Membrane cofactor protein isoform 14 (CD46), is a type I membrane protein which has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 vital for regulation. CD46 is also involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 is common in thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm.
Product Name Alternative
AHUS2||MCP||MIC10||TLX||TRA2.10||Membrane cofactor protein||Trophoblast leukocyte common antigen||CD46.
Purification
Greater than 85% as determined by SDS-PAGE.
Components
CD46 protein solution (0.5mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 20% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

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