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Alpha Actinin Native Protein

CAT: 0793-32-3176-50Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0793-32-3176-50Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Chicken Gizzard. Ultra pure Alpha Actinin having a Molecular mass of 95,000 Dalton. ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
Product Name Alternative
Alpha-actinin-1||Alpha-actinin cytoskeletal isoform||Non-muscle alpha-actinin-1||F-actin cross-linking protein||ACTN1.
Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Components
The protein was lyophilized from a 1mg/mL solution containing 10mM Tris acetate buffer pH 7.6, 0.1mM EDTA, 2mM DTT, and 20mM NaCl.
Storage Conditions
Lyophilized a-Actinin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution a-Actinin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.
Applications Notes
It is recommended to reconstitute the lyophilized a-Actinin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.

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Alternative Products

CatalogName
B2016498Native Chicken Alpha Actinin 1
PROTP05094-01A-Actinin Actinin Alpha protein
OPPA01409-10UGA-Actinin - Alpha Actinin Protein
30R-2105Alpha Actinin protein
NBL1-07282alpha-Actinin 1 Overexpression Lysate (Native) - (Dry Ice)
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304599-01ACTN1/ACTN2/ACTN3/ACTN4 (pan-alpha-Actinin, alpha-Actinin-pan, Actinin-alpha, Actinin alpha, alpha Actinin, alpha-Actinin, Alpha-Actinin-4, F-Actin cross-linking Protein, Non-muscle alpha-Actinin 4, ACTN4, alpha-Actinin4, Actinin alpha4, Actininalpha4, alphaActinin-4, Actinin-alpha4, alpha-Actinin-4, Alpha-Actinin-1, Alpha-Actinin Cytoskeletal Isoform, Non-muscle alpha-Actinin-1, ACTN1, alpha-Actinin1, Actinin alpha1, Actininalpha1, alphaActinin-1, Actinin-alpha1, alpha-Actinin-1, Alpha-Actinin-2, Alpha-Actinin skeletal muscle Isoform 2, ACTN2, alpha-Actinin2, Actinin alpha2, Actininalpha2, alphaActinin-2, Alpha-Actinin-3, Alpha-Actinin skeletal muscle Isoform 3, ACTN3, alpha-Actinin3, Actinin alpha3, Actininalpha3, alphaActinin-3, Actinin-alpha3, alpha-Actinin-2, alpha-Actinin-3)
220570-01Actinin, alpha1/2/3/4 (pan-alpha-Actinin, alpha-Actinin-pan, Actinin-alpha, Actinin alpha, alpha Actinin, alpha-Actinin, Alpha-Actinin-4, F-Actin cross-linking Protein, Non-muscle alpha-Actinin 4, ACTN4, alpha-Actinin4, Actinin alpha4, Actininalpha4, alphaActinin-4, Actinin-alpha4, alpha-Actinin-4, Alpha-Actinin-1, Alpha-Actinin Cytoskeletal Isoform, Non-muscle alpha-Actinin-1, ACTN1, alpha-Actinin1, Actinin alpha1, Actininalpha1, alphaActinin-1, Actinin-alpha1, alpha-Actinin-1, Alpha-Actinin-2, Alpha-Actinin skeletal muscle Isoform 2, ACTN2, alpha-Actinin2, Actinin alpha2, Actininalpha2, alphaActinin-2, Alpha-Actinin-3, Alpha-Actinin skeletal muscle Isoform 3, ACTN3, alpha-Actinin3, Actinin alpha3, Actininalpha3, alphaActinin-3, Actinin-alpha3, alpha-Actinin-2, alpha-Actinin-3) discontinued
30R-AA001Alpha Actinin protein (Chicken)
GTR18887331-01Human alpha Actinin protein

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