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UBE2D1 Recombinant Protein

CAT: 0793-32-2882-20Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2882-20Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. UBE2D1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (1-147 a.a.) and having a molecular mass of 19kDa.UBE2D1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. UBE2D1 is a member of the ubiquitin-conjugating enzyme family. Ubiquitination involves at least 3 classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . UBE2D1 is strongly related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. In addition, UBE2D1 functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Product Name Alternative
Ubiquitin-conjugating enzyme E2 D1||Stimulator of Fe transport||SFT||UBC4/5 homolog||UbcH5||Ubiquitin carrier protein D1||Ubiquitin-conjugating enzyme E2 (17) KB 1||Ubiquitin-conjugating enzyme E2-17 kDa 1||Ubiquitin-protein ligase D1||UBE2D1||SFT||UBC
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
UBE2D1 solution (1mg/mL) containing 20mM Tris-HCl buffer (pH8.0), 40% glycerol and 0.1M NaCl.
Storage Conditions
UBE2D1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MGSMALKRIQ KELSDLQRDP PAHCSAGPVG DDLFHWQATI MGPPDSAYQG GVFFLTVHFP TDYPFKPPKI AFTTKIYHPN INSNGSICLD ILRSQWSPAL TVSKVLLSIC SLLCDPNPDD PLVPDIAQIY KSDKEKYNRH AREWTQKYAM.