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PPP3R1 Recombinant Protein

CAT: 0793-32-2723-20Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2723-20Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. PPP3R1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids (1-170.a.a) and having a molecular mass of 21.5kDa. PPP3R1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PPP3R1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase which takes a vital part in the T cell activation pathway. Calcineurin is composed of two subunits; calcineurin A (CnA) and calcineurin B (CnB) . Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells.
Product Name Alternative
Protein phosphatase 3 regulatory subunit B alpha||CNB1||CALNB1||Protein phosphatase 3 (formerly 2B) regulatory subunit B (19kD) alpha isoform (calcineurin B type I) ||Calcineurin B type I (19kDa) .
Purification
Greater than 90% as determined by SDS-PAGE.
Components
PPP3R1 Human solution (1mg/1ml) containing 20mM Trsi HCL pH-8, 0.1M NaCl, 2mM DTT and 10% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MGNEASYPLE MCSHFDADEI KRLGKRFKKL DLDNSGSLSV EEFMSLPELQ QNPLVQRVID IFDTDGNGEV DFKEFIEGVS QFSVKGDKEQ KLRFAFRIYD MDKDGYISNG ELFQVLKMMV GNNLKDTQLQ QIVDKTIINA DKDGDGRISF EEFCAVVGGL DIHKKMVVDV

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