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PLA2G1B Recombinant Protein

CAT: 0793-32-2678-10Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2678-10Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. Secreted Phospholipase A2-IB Human Recombinant is manufactured with N-terminal fusionf HisTag. PLA2G1B His-Tagged Fusion Protein is 16 kDa containing 126 amino acid residues of the human secreted phospholipase A2-IB and 16 additional amino acid residues - HisTag .MRGSHHHHHH GMASHMAVWQ FRKMIKCVIP GSDPFLEYNN YGCYCGLGGS GTPVDELDKC CQTHDNCYDQ AKKLDSCKFL LDNPYTHTYS YSCSGSAITC SSKNKECEAF ICNCDRNAAI CFSKAPYNKA HKNLDTKKYC QS. Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense.
Product Name Alternative
Phospholipase A2||EC 3.1.1.4||Phosphatidylcholine 2-acylhydrolase||Group IB phospholipase A2||PLA2||PLA2A||PPLA2||sPLA2-IB, MGC119834||MGC119835||PLA2G1B.
Purification
Greater than 95% as determined by SDS-PAGE.
Components
Concentration 0.15 mg/mL in PBS
Storage Conditions
Store protein at -20°C. Aliquot the product to avoid repeated freezing/thawing cycles. Protein can be stored at 4°C for a limited period of time.
Applications Notes
Add PBS to prepare a working stock solution. Product is sterile.
Amino Acids
MRGSHHHHHH GMASHMAVWQ FRKMIKCVIP GSDPFLEYNN YGCYCGLGGS GTPVDELDKC CQTHDNCYDQ AKKLDSCKFL LDNPYTHTYS YSCSGSAITC SSKNKECEAF ICNCDRNAAI CFSKAPYNKA HKNLDTKKYC QS.

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